Birdshot retinochoroidopathy is a clinically distinct pattern of posterior segment inflammation of presumed autoimmune etiology.
The characteristic spots of depigmentation, usually cream-colored at the level of the retinal pigment epithelium or deeper, are the most distinctive sign of birdshot retinochoroidopathy. The lesions radiate outwards from the disc in a linear pattern that seems to follow the choroidal vessels.
The differential diagnosis includes other entities that produce a chronic mild to moderate bilateral panuveitis with choroidal infiltrates. Studies have demonstrated that more than 90% of patients with Birdshot Retinochoroidopathy have HLA-A29 and may be an indicator for evaluation and diagnosis of the disease in patients with suggestive ocular symptoms.
References
Chang B., Lumbroso L, Rabb MF, Yannuzzi LA. Birdshot chorioretinopathy. In: Yannuzzi LA, Flower RW, Slakter JS, eds. Indocyanin Green Angiography, 1st ed.St.Louis: Mosby, 1997:231-238.